Our Mission is to Give Patients Back More of Their Own Skin to Make Them Well Again: Dr. Daniela Marino, CEO of CUTISS

Established in 2017, CUTISS is a Swiss clinical-stage life sciences company focused on regenerative medicine, tissue engineering, and skin pigmentation. Dedicated to advancing treatments for individuals with severe skin injuries or disorders, it has embraced a purpose-driven mission to alleviate suffering and improve lives through cutting-edge solutions.

The flagship product of the company, denovoSkin™, exemplifies precision and dedication in regenerative medicine. It is a bioengineered dermo-epidermal skin graft developed from a small biopsy of the patient’s healthy skin. This approach minimizes the complications associated with traditional skin grafting methods, offering a tailored solution to burn victims and individuals with extensive skin defects. The process behind denovoSkin™ underscores meticulous attention to detail, combining advanced cell biology and tissue engineering to replicate the structure and function of natural skin.

Developing denovoSkin™ required overcoming complex scientific challenges. The team at CUTISS has expertly utilized autologous cells to create grafts that integrate seamlessly with the patient’s body. The result is a product that not only addresses aesthetic concerns but also restores critical physiological functions. This innovation has opened new avenues for treatment, particularly for patients who previously faced limited options.

The scalability of denovoSkin™ reflects the company’s ability to adapt its technologies for widespread clinical application. CUTISS has implemented automated production processes that streamline manufacturing without compromising quality. This advancement ensures a consistent supply of high-quality grafts, addressing a growing demand for personalized regenerative treatments. The integration of automation also allows for greater efficiency, reducing production time and cost while maintaining the rigorous standards necessary for medical applications.

Clinical trials have been instrumental in validating the effectiveness and safety of denovoSkin™. The results have demonstrated significant improvements in wound healing, reduced scarring, and enhanced patient outcomes. These trials have provided the foundation for regulatory approvals and established the product as a reliable option for addressing complex skin injuries. Physicians and patients alike have recognized the potential of this technology to transform care standards in dermatology and reconstructive surgery.

Collaboration has played a pivotal role in the company’s journey. By forging partnerships with leading research institutions, hospitals, and industry experts, the company has created a robust ecosystem that fosters continuous innovation. These alliances have facilitated knowledge exchange and provided the necessary resources to accelerate product development. Additionally, the company has benefited from strategic support, including funding and mentorship, which has enabled it to navigate the intricate pathways of medical innovation.

CUTISS operates with a strong emphasis on sustainability and ethical responsibility. The manufacturing processes align with environmentally conscious practices, reflecting a commitment to minimizing waste and resource use. Ethical considerations have also been paramount in every stage of development, from research to patient care. This conscientious approach has reinforced trust and credibility among stakeholders.

The company’s leadership has been instrumental in steering its vision forward. Guided by a team of seasoned professionals with expertise in biotechnology and business management, the organization has successfully translated research into real-world impact. This leadership has cultivated a culture of excellence, encouraging innovation while ensuring operational integrity.

The market potential for personalized skin grafts continues to expand, driven by rising demand for effective treatments for burns, chronic wounds, and other skin conditions. CUTISS is well-positioned to address this demand through its groundbreaking technology. By prioritizing patient-specific solutions, the company has established a distinct identity in the competitive field of regenerative medicine. This focus on personalization ensures that treatments are not only clinically effective but also aligned with the unique needs of individuals.

Future developments are poised to extend the applications of the company’s technology. Research is underway to explore additional uses for bioengineered skin, including cosmetic applications and treatments for rare genetic skin disorders. These efforts highlight the versatility of the platform and its potential to address a broader spectrum of medical needs.

As CUTISS continues its journey, the emphasis remains on delivering measurable benefits to patients while advancing the boundaries of biotechnology. The company exemplifies the potential of science to address complex medical challenges through innovative solutions. By combining expertise, ethical practices, and a patient-centric approach, it has set a benchmark for excellence in personalized medicine.

This commitment to progress reflects a deep understanding of the profound impact that regenerative treatments can have on individuals and communities. CUTISS has not only introduced a transformative product but also demonstrated the broader possibilities of merging biotechnology with compassion.

Dr. Daniela Marino, Co-Founder & CEO, CUTISS

“Our team consists of over 40 employees, top notch senior executives, advisors and investors. It includes scientists, medical doctors, GMP manufacturers, translational researchers and regulatory experts, clinical trial managers, as well as product and business development and industrial expertise.”